## ---- include = FALSE--------------------------------------------------------- knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) ## ----setup-------------------------------------------------------------------- library(biogrowth) library(tidyverse) ## ----------------------------------------------------------------------------- data("growth_salmonella") head(growth_salmonella) ## ----------------------------------------------------------------------------- fit1 <- fit_growth(growth_salmonella, list(primary = "Baranyi"), start = c(lambda = 0, logNmax = 8, mu = .1, logN0 = 2), known = c(), environment = "constant" ) ## ----------------------------------------------------------------------------- fit2 <- fit_growth(growth_salmonella, list(primary = "Baranyi"), start = c(logNmax = 8, mu = .1, logN0 = 2), known = c(lambda = 0), environment = "constant" ) ## ----------------------------------------------------------------------------- fit3 <- fit_growth(growth_salmonella, list(primary = "modGompertz"), start = c(C = 8, mu = .1, logN0 = 2, lambda = 0), known = c(), environment = "constant" ) ## ----------------------------------------------------------------------------- my_models <- list( Baranyi = fit1, `Baranyi no-lag` = fit2, `mod Gompertz` = fit3 ) salmonella_models <- compare_growth_fits(my_models) ## ----------------------------------------------------------------------------- print(salmonella_models) ## ---- fig.width=6------------------------------------------------------------- plot(salmonella_models) ## ---- fig.width=6------------------------------------------------------------- plot(salmonella_models, type = 2) + theme(axis.text.x = element_text(angle = 45, hjust = 1)) ## ---- fig.width=6------------------------------------------------------------- plot(salmonella_models, type = 3) ## ----------------------------------------------------------------------------- summary(salmonella_models) ## ----------------------------------------------------------------------------- coef(salmonella_models) ## ----------------------------------------------------------------------------- data("multiple_counts") data("multiple_conditions") sec_models <- list(temperature = "CPM", pH = "CPM") known_pars <- list(Nmax = 1e8, N0 = 1e0, Q0 = 1e-3, temperature_n = 2, temperature_xmin = 20, temperature_xmax = 35, pH_n = 2, pH_xmin = 5.5, pH_xmax = 7.5, pH_xopt = 6.5, temperature_xopt = 30) my_start <- list(mu_opt = .8) global_fit <- fit_growth(multiple_counts, sec_models, my_start, known_pars, environment = "dynamic", algorithm = "regression", approach = "global", env_conditions = multiple_conditions ) sec_models <- list(temperature = "CPM", pH = "CPM") known_pars <- list(Nmax = 1e8, N0 = 1e0, Q0 = 1e-3, temperature_n = 1, temperature_xmin = 20, temperature_xmax = 35, pH_n = 2, pH_xmin = 5.5, pH_xmax = 7.5, pH_xopt = 6.5, temperature_xopt = 30) my_start <- list(mu_opt = .8) global_fit2 <- fit_growth(multiple_counts, sec_models, my_start, known_pars, environment = "dynamic", algorithm = "regression", approach = "global", env_conditions = multiple_conditions ) ## ----------------------------------------------------------------------------- global_comparison <- compare_growth_fits(list(`n=2` = global_fit, `n=1` = global_fit2)) ## ---- fig.width=6------------------------------------------------------------- plot(global_comparison) ## ---- fig.width=6------------------------------------------------------------- plot(global_comparison, type = 3) ## ---- fig.width=6------------------------------------------------------------- print(global_comparison) plot(global_comparison, type = 2) summary(global_comparison) coef(global_comparison) ## ----------------------------------------------------------------------------- data("example_cardinal") head(example_cardinal) ## ----------------------------------------------------------------------------- sec_model_names <- c(temperature = "Zwietering", pH = "CPM") known_pars <- list(mu_opt = 1.2, temperature_n = 1, pH_n = 2, pH_xmax = 6.8, pH_xmin = 5.2) my_start <- list(temperature_xmin = 5, temperature_xopt = 35, pH_xopt = 6.5) fit1 <- fit_secondary_growth(example_cardinal, my_start, known_pars, sec_model_names) known_pars <- list(mu_opt = 1.2, temperature_n = 2, pH_n = 2, pH_xmax = 6.8, pH_xmin = 5.2) fit2 <- fit_secondary_growth(example_cardinal, my_start, known_pars, sec_model_names) ## ----------------------------------------------------------------------------- my_models <- list(`n=1` = fit1, `n=2` = fit2) secondary_comparison <- compare_secondary_fits(my_models) ## ---- fig.width=6------------------------------------------------------------- print(secondary_comparison) plot(secondary_comparison) plot(secondary_comparison, type = 2) coef(secondary_comparison) summary(secondary_comparison)